Outbreak of dengue fever in Haripur, Khyber Pakhtunkhwa, Pakistan
Keywords:dengue fever, virus, flavivirus, Haripur, human
BACKGROUND. Dengue fever is caused by single-stranded RNA virus belonging to the flavivirus group. Every year, roughly 2.5 billion people around the world are affected from dengue fever. Current study aimed to evaluate the burden of dengue fever in Haripur and was conducted at the District Hospital and the Department of Medical Laboratory Technology, University of Haripur, KPK. METHODS. Three ml of venous blood was collected from patients by venipuncture and immune-chromatographic (ICT) techniques were used. Data was analyzed using Excel worksheet. RESULTS. Total of 173, 177, 145, 96, 187 and 166 cases in both male and female patients were reported during years 2010, 2011, 2012, 2013, 2014 and 2015 respectively. Out of 173 affected persons in 2010, total 49.1% were males and 36.4% females. Similarly, in 2011, out of 177 penitents, 14.6% were males and 6.7% were females affected by dengue fever. In 2012, out of 145 affected persons, 8.9% were males and 10.3% were females, while in years 2014 and 2015 there were 10.1% males and 12.8% females and 5.4% males and 3.6% females affected by dengue fever respectively. High prevalence was noted from August to October in Pakistan. Higher frequency in males as compared to females was observed in the study area. CONCLUSION. Awareness about dengue virus and sensitization should be conducted in affected areas to ensure maximum protection and reduce the morbidity of the disease.
2. Yang HM, Macoris ML, Galvani KC, Andrighetti MT, Wanderley DM. Assessing the effects of temperature on the population of Aedes aegypti, the vector of dengue. Epidemiology and infection. 2009; 137 (8): 1188-1202. doi: 10.1017/s0950268809002040.
3. Guzman MG, Harris E. Dengue. Lancet (London, England). 2015; 385 (9966): 453-465. doi: 10.1016/s0140-6736(14)60572-9.
4. Hurtado-Diaz M, Riojas-Rodriguez H, Rothenberg SJ, Gomez-Dantes H, Cifuentes E. Short communication: impact of climate variability on the incidence of dengue in Mexico. Tropical medicine & international health : TM & IH. 2007; 12 (11): 1327-1337. doi: 10.1111/j.1365-3156.2007.01930.x.
5. Gupta E, Dar L, Kapoor G, Broor S. The changing epidemiology of dengue in Delhi, India. Virology journal. 2006; 3: 92. doi: 10.1186/1743-422x-3-92.
6. Kularatne S, Seneviratne S, Malavige G, Fernando S, Velathanthiri V, Ranatunga P, Wijewickrama E, Gurugama P, Karunatilaka D, Aaskov J. Synopsis of findings from recent studies on dengue in Sri Lanka. Dengue Bulletin. 2006; 30: 80.
7. Jawad K, Masood S, Tassawar H, Inam B, Waheeduz Z. Outbreak of dengue hemorrhagic fever in Karachi. Pak Armed Forces Med J. 2001; 51 (2): 94-98.
8. Akram DS, Igarashi A, Takasu T. Dengue virus infection among children with undifferentiated fever in Karachi. Indian journal of pediatrics. 1998; 65 (5): 735-740.
9. Gubler DJ. Dengue and dengue hemorrhagic fever. Clinical microbiology reviews. 1998; 11 (3): 480-496.
10. Paul RE, Patel AY, Mirza S, Fisher-Hoch SP, Luby SP. Expansion of epidemic dengue viral infections to Pakistan. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 1998; 2 (4): 197-201.
11. Strobel M, Lamaury I. [Dengue fever: a review]. La Revue de medecine interne. 2001; 22 (7): 638-647.
12. Keating J. An investigation into the cyclical incidence of dengue fever. Social science & medicine (1982). 2001; 53 (12): 1587-1597.
13. Khan E, Siddiqui J, Shakoor S, Mehraj V, Jamil B, Hasan R. Dengue outbreak in Karachi, Pakistan, 2006: experience at a tertiary care center. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2007; 101 (11): 1114-1119. doi: 10.1016/j.trstmh.2007.06.016.
14. Khan E, Kisat M, Khan N, Nasir A, Ayub S, Hasan R. Demographic and clinical features of dengue fever in Pakistan from 2003-2007: a retrospective cross-sectional study. PloS one. 2010; 5 (9): e12505. doi: 10.1371/journal.pone.0012505.
15. Humayoun MA, Waseem T, Jawa AA, Hashmi MS, Akram J. Multiple dengue serotypes and high frequency of dengue hemorrhagic fever at two tertiary care hospitals in Lahore during the 2008 dengue virus outbreak in Punjab, Pakistan. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2010; 14 Suppl 3: e54-59. doi: 10.1016/j.ijid.2009.10.008.
16. Farhana R, Awatef KF, Khanum H, Akter T. Prevalence of dengue fevers among the patients of different economic status attended at local hospital in Dhaka. Bangladesh Journal of Zoology. 2014; 42 (2): 161-168.
17. Rashmi K, Ravikumar K, Pratibha MJ, Giridhar UP, Arun KR. Serological markers prevalence and trend of probable dengue infection at a tertiary care hospital in Bangalore. Journal of Evolution of Medical and Dental Sciences. 2013; 2 (36): 6968-6977.
18. Khan J, Khan A. Incidence of dengue in 2013: dengue outbreak in District Swat, Khyber Pakhtunkhwa, Pakistan. Inter J of Fauna and Biolo Stud. 2015; 2 (1): 1-7.
19. Khan J, Munir W, Khan B, Ahmad Z, Shams W, Khan A. Dengue outbreak 2013: Clinical profile of patients presenting at DHQ Burner and THQ Shangla, Khyber Pakhtunkhwa, Pakistan. Immunity & Diseases. 2015; 3 (11).
20. Ikhlak U, Irfan M, Ali S, Ashraf A, Xiao S, Qayyum M. Prevalence of Dengue in Students of Arid Agriculture University Rawalpindi. PSM Microbiology. 2016; 1 (2): 62-65.
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