Biology and genetics of colorectal cancer


  • Danijel Brletić Department of Surgery, Clinical Hospital Center "Sestre milosrdnice"



colorectal neplasms, cancer genes, genes, tumor suppressing, Adenomatous Polyposis Coli, Attenuated familial adenomatous polyposis, Colorectal neoplasms, hereditary nonpolyposis


Colorectal cancer is one of the most common malignant tumors. The frequency and potential for prevention put colorectal cancer at the center of attention of oncologists around the world. Malignant transformation is the result of the accumulation of mutations of numerous genes that are critical to regulating cell growth and differentiation, either due to increasing of the rate of mutations or due to the damage of DNA repair mechanisms. In this review, we discuss biology and genetics of colorectal cancer.


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How to Cite

Brletić, D. (2017). Biology and genetics of colorectal cancer. BioMedicine and Surgery, 1(2), 77–83.