Liver resection for colorectal cancer liver metastases


  • Jamin Kashwa Department of Surgery, Homerton University Hospital, UK



colorectal cancer, secondary liver tumors, liver resection


Surgery is the only potentially curative treatment of colorectal cancer liver metastases. Important change in the surgical treatment of colorectal cancer liver metastases took place in the last two decades. Due to advancement in diagnostic methods more patients can be surgically treated in the earlier phase of disease and advancement in surgical technique and the development of new surgical instruments enabled safer complex resections with minimal blood loss. Because of complex liver vascular supply, thorough knowledge of inner hepatic anatomy is of utmost importance for performing resections. Indications for liver resection in patients with colorectal cancer metastases underwent fundamental changes so today the number, size and distribution of metastases in the liver are no longer important. The only contraindication for liver resection is the inability to preserve sufficient volume of functional liver parenchyma after resection that enables more patients to undergo potentially curative surgical treatment. In patients with initially inoperable liver metastases there are other methods for destruction of liver metastases, such as radiofrequency ablation or high-intensity focused ultrasound, and regenerative capability of the liver enables repeated surgical procedures with five year survival that reaches 40%. Bleeding during liver resection, that was a major problem in the past, has been nowadays reduced to minimum with techniques such as reducing central venous pressure, new devices for liver resection and the usage of local hemostatics.


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How to Cite

Kashwa, J. (2017). Liver resection for colorectal cancer liver metastases. BioMedicine and Surgery, 1(1), 16–23.